tag:blogger.com,1999:blog-827769867360256958.post987851373586338483..comments2024-01-14T03:16:09.597-08:00Comments on Kindke's Scrap Notes: Food - can it shift the Circadian Rythm?Kindkehttp://www.blogger.com/profile/15841418412425329998noreply@blogger.comBlogger2125tag:blogger.com,1999:blog-827769867360256958.post-23717676990383818832012-02-19T11:34:38.590-08:002012-02-19T11:34:38.590-08:00Dunno why you cant see it Wooo, might be country r...Dunno why you cant see it Wooo, might be country restricted, theres alot of videos I cant watch just because im in UK and there are copyright issues.<br /><br />I did come across alot of Ghrelin stuff in my earlier blogging days, Ghrelin helps with slow-wave sleep, the guy on leangains.com posted a study showing a strong link with ghrelin and circadian rhythm.<br /><br />The most interesting find though was a study measuring ghrelin over 24hours in both lean and obese people.<br /><br />In lean people, there was a massive spike in ghrelin during bedtime and sleeping hours, which did not occur with the obese people, one has to wonder what horrible side affects that has for fatties -.-<br /><br /><br />This is the study<br /><br />http://www.ncbi.nlm.nih.gov/pubmed/15231997Kindkehttps://www.blogger.com/profile/15841418412425329998noreply@blogger.comtag:blogger.com,1999:blog-827769867360256958.post-44782821632985854662012-02-18T14:45:24.363-08:002012-02-18T14:45:24.363-08:00Bah it would not let me watch it :( Says I can'...Bah it would not let me watch it :( Says I can't from my current location?<br /><br />Actually ghrelin (which ties into onset of meal time) is believed to directly modulate the circadian rhythm. <br /><br />Ghrelin also affects mood and motivation (dopamine).<br /><br />Ghrelin is very significantly controlled by insulin levels, and a hallmark of obesity is Ghrelin is always low, even after an overnight fast, as abnormal hyperinsulinemia keeps the endocrine system constantly locked in a fed state (so ghrelin does not decline normally).<br /><br />There was a time I was considering a link between suppressed chronically low ghrelin and some of the depressive symptoms I experience eating a "normal" insulinogenic diet. I think ghrelin is involved because I experienced low grade dysphoria early on in leptin therapy, and leptin also powerfully suppresses ghrelin. I also seem to have circadian rhythm component due to amelioration of symptoms with light therapy.<br /><br />I have sort of abandoned doing more research into this but my intuition is that ghrelin is quite important in mood and motivation, and when it is too low (e.g. obesity and hyperinsulinemia) the person may be given to apathy and dysphoria .ItsTheWooohttps://www.blogger.com/profile/12057537399918684119noreply@blogger.com