Wednesday, 29 June 2011

Cooling the brain and insomnia

Cooling the Brain During Sleep May Be a Natural and Effective Treatment for Insomnia

Monday, 27 June 2011

β-Hydroxybutyrate is the preferred substrate for GABA

β-Hydroxybutyrate is the preferred substrate for GABA and glutamate synthesis while glucose is indispensable during depolarization in cultured GABAergic neurons.

Tuesday, 7 June 2011

Mitochondrial Uncoupling

The ketogenic diet increases mitochondrial glutathione levels.

"Together, the results demonstrate that the KD up-regulates GSH biosynthesis, enhances mitochondrial antioxidant status, and protects mtDNA from oxidant-induced damage."

I also found this study recently which was interesting.....

Glutathionylation acts as a control switch for uncoupling proteins UCP2 and UCP3.

The two are related it seems, i think it presents a novel explanation for uncoupling protein increase on a ketogenic diet.