Thursday, 15 July 2010

Going to bed in a insulin sensitive state

Im still intrigued by the study posted recently were lean subjects got a spike in ghrelin during sleeping hours and obese subjects didnt.

In the study, the subjects were eating high carb meals all day, in the last 2 meals they had a blunted response to ghrelin, suggesting that they may be insulin resistent at this point. Going to bed in an insulin resistent state is perhaps not sufficient to make a ghrelin response becuase ghrelin itself will cause a kind of physiological insulin resistence so that we can switch to FFA for fuel.

This is just trial and error and speculation at the moment, tomorrow I will look for more studies to piece together the puzzle of ghrelin.

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