Uncoupling proteins - all is not as it seems......

Uncoupling Protein 2 Negatively Regulates Glucose-Induced Glucagon-Like Peptide-1 (GLP-1) Secretion.

Variation in The Uncoupling Protein 2 and 3 Genes and Human Performance.

Further Support to the Uncoupling-to-Survive Theory: The Genetic Variation of Human UCP Genes Is Associated with Longevity.

Effects of dairy consumption on SIRT1 and mitochondrial biogenesis in adipocytes and muscle cells.

Polymorphisms of the UCP2 gene are associated with body fat distribution and risk of abdominal obesity in Spanish population.

Mitochondrial uncoupling protein 2 (UCP2) in glucose and lipid metabolism.

The role of uncoupling protein 2 (UCP2) on the development of type 2 diabetes mellitus and its chronic complications.

"This uncoupling effect then leads to homologue- and tissue-specific functions, such as thermogenesis (UCP1), regulation of FFAs metabolism and transport (UCP2 and UCP3), reduction in ROS formation (UCP1-3 and UCP5/BMCP1), and regulation of ATP-dependent processes (UCP2)"

G protein-coupled receptors: Case builds for TGR5 as metabolic syndrome target.