Saturday, 6 August 2011

Insulin responsible for poor incretin response?

Insulin-dependent suppression of cholesterol 7α-hydroxlase is a possible link between glucose and cholesterol metabolisms.

cholesterol 7a-hydroxlase is the rate-limiting step for the synthesis of bile acids from cholesterol.

Is this why obese people have high cholesterol and poor postprandial bile acid/incretin responses?

Food for thought anyway.

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