http://www.ncbi.nlm.nih.gov/pubmed/19356713
Also this excellent thread explains alot http://forum.lowcarber.org/showthread.php?t=394793&page=1&pp=15
Monday, 8 November 2010
Saturday, 6 November 2010
Diet-induced ketosis increases capillary density without altered blood flow in rat brain.
http://www.ncbi.nlm.nih.gov/pubmed/17284577
Also we have
http://www.ncbi.nlm.nih.gov/pubmed/16594134
"These data indicate that adaptation to hypoxia did not interfere with ketosis, and that ketosis during hypoxia may lower lactate levels in brain, suggesting decreased glycolysis or increased glucose disposal."
Also we have
http://www.ncbi.nlm.nih.gov/pubmed/16594134
"These data indicate that adaptation to hypoxia did not interfere with ketosis, and that ketosis during hypoxia may lower lactate levels in brain, suggesting decreased glycolysis or increased glucose disposal."
Immediate metabolic availability of dietary fat in combination with carbohydrate.
http://www.ncbi.nlm.nih.gov/pubmed/8279403
After reading all the related studies on a pubmed search to this study, it is clear that dietary fat is handled before dietary carbs if combined in the same meal.
Further, it appears that dietary fat is primed for usage as fuel immediately, and that adipocytes promptly actually start taking up FFA from the blood to reform them into trigs.
After reading all the related studies on a pubmed search to this study, it is clear that dietary fat is handled before dietary carbs if combined in the same meal.
Further, it appears that dietary fat is primed for usage as fuel immediately, and that adipocytes promptly actually start taking up FFA from the blood to reform them into trigs.
Preferential uptake of dietary Fatty acids in adipose tissue and muscle in the postprandial period.
http://www.ncbi.nlm.nih.gov/pubmed/17192479
"In this study, the most striking findings were the postprandial uptake of fatty acids from the circulating NEFA pool by adipose tissue, the direct confirmation that chylomicrons are the preferred substrate of LPL over VLDL, the preferential channeling of fatty acids derived from LPL-mediated chylomicron hydrolysis into adipose tissue, and the postprandial release of fatty acids across the forearm."
So it looks like it is bad news to combine meals that are both high in fat and carbs. The result will be lots of vLDL particules swimming around in your blood.
"In this study, the most striking findings were the postprandial uptake of fatty acids from the circulating NEFA pool by adipose tissue, the direct confirmation that chylomicrons are the preferred substrate of LPL over VLDL, the preferential channeling of fatty acids derived from LPL-mediated chylomicron hydrolysis into adipose tissue, and the postprandial release of fatty acids across the forearm."
So it looks like it is bad news to combine meals that are both high in fat and carbs. The result will be lots of vLDL particules swimming around in your blood.
Friday, 5 November 2010
The Hexosamine Pathway
Currently there is no wikipedia page for this part of biochemistry and knowledge of it still appears to be developing. It seems to be related to insulin signalling and insulin resistence, and over-expression of the pathway seems to cause IR as suggested by this paper.
This next study was also an interesting find, some AA's are produced in vivo in adipocytes, glutamine being one.
http://www.ncbi.nlm.nih.gov/pubmed/1851687
This next study was also an interesting find, some AA's are produced in vivo in adipocytes, glutamine being one.
http://www.ncbi.nlm.nih.gov/pubmed/1851687
Tuesday, 2 November 2010
Its still working
Still having good success with the below training protocol. After using it for the leg press I suffered severe DOMS for 3 days , 2 of those days i could barely walk.
However, I did feel a good response in hypertrophy. My quads and hamstrings felt noticably bigger, just from 1 session.
However, I did feel a good response in hypertrophy. My quads and hamstrings felt noticably bigger, just from 1 session.
Monday, 25 October 2010
Effective training method that defies the science
Started trying a new method of training recently that seems to be getting surprisingly good results. The method is to use a resistence that is about 50% of your 1RM, perform 10 reps at a nice and controlled pace of about 2 seconds up, 2 seconds down, then rest for only about 30 seconds between sets.
Repeat this until you come to failure but adjust the weight if you cant do atleast 5 sets.
Ideally you should come to failure after 5 sets at around 55-65 reps in total. At this point stop, and move onto the next exercise.
This method of training is interesting to me becuase the short rest periods means you keep the intensity and focus on your training high, rather than waiting 3-5 mins between sets and day dreaming. Its also very effecient you can do a whole body workout in a short amount of time and avoids being seen as a machine hogger at the gym. My gym gets so overcrowded all the time so this fast training fits in with it.
Its difficult to say why this method of training is so effective when trying to explain it from the known science of muscle anatomy and hypertrophy. Using a weight of only about 50% means you hit most of the fibres quite hard, and going to failure means you hit all the different motor neuron sizes.
Further, in reps 30-50 you keep the muscle in a pro-longed state of high acidosis. The total time here is the time it takes to complete reps 30-40, plus 30 seconds rest, plus 40-50 reps, plus 30 seconds, then another 5 reps or so to failure, then it will take about 2-3 minutes for the muscle to recover from the acidosis.
In comparison to just doing 3 sets of 20 reps with 3 mins rest, there are gaps in the state of acidosis here.
Repeat this until you come to failure but adjust the weight if you cant do atleast 5 sets.
Ideally you should come to failure after 5 sets at around 55-65 reps in total. At this point stop, and move onto the next exercise.
This method of training is interesting to me becuase the short rest periods means you keep the intensity and focus on your training high, rather than waiting 3-5 mins between sets and day dreaming. Its also very effecient you can do a whole body workout in a short amount of time and avoids being seen as a machine hogger at the gym. My gym gets so overcrowded all the time so this fast training fits in with it.
Its difficult to say why this method of training is so effective when trying to explain it from the known science of muscle anatomy and hypertrophy. Using a weight of only about 50% means you hit most of the fibres quite hard, and going to failure means you hit all the different motor neuron sizes.
Further, in reps 30-50 you keep the muscle in a pro-longed state of high acidosis. The total time here is the time it takes to complete reps 30-40, plus 30 seconds rest, plus 40-50 reps, plus 30 seconds, then another 5 reps or so to failure, then it will take about 2-3 minutes for the muscle to recover from the acidosis.
In comparison to just doing 3 sets of 20 reps with 3 mins rest, there are gaps in the state of acidosis here.
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