Cooling the brain and insomnia

Cooling the Brain During Sleep May Be a Natural and Effective Treatment for Insomnia

http://www.sciencedaily.com/releases/2011/06/110613093502.htm

β-Hydroxybutyrate is the preferred substrate for GABA

β-Hydroxybutyrate is the preferred substrate for GABA and glutamate synthesis while glucose is indispensable during depolarization in cultured GABAergic neurons.

http://www.ncbi.nlm.nih.gov/pubmed/21684314

Mitochondrial Uncoupling

The ketogenic diet increases mitochondrial glutathione levels.

"Together, the results demonstrate that the KD up-regulates GSH biosynthesis, enhances mitochondrial antioxidant status, and protects mtDNA from oxidant-induced damage."

I also found this study recently which was interesting.....

Glutathionylation acts as a control switch for uncoupling proteins UCP2 and UCP3.

The two are related it seems, i think it presents a novel explanation for uncoupling protein increase on a ketogenic diet.

Advice and Confidence - Dan Ariely

Dan Ariely has some truely amazing and shocking revelations on his site here, but since I have spent the last few months trading I was particularly interested in these 2 articles,

http://www.psychologytoday.com/blog/predictably-irrational/200907/the-value-advice

http://www.psychologytoday.com/blog/predictably-irrational/200907/were-more-swayed-confidence-expertise

The bottom line is, advice from sources we presume to be more informed than us pretty much shuts down our brains own decision making machinery.

Also, we find confidence far more seducing than expertise.

Thigh, Bum and Belly Fat Differentials

http://www.ncbi.nlm.nih.gov/pubmed/20682685

This study suggests that overall flux of fat into thigh/bum area is less easily done as compared into the belly area, and the belly area more easily takes up dietary fat compared to thigh/bum fat.

2,4-Dinitrophenol - The anti obesity drug thats been known since 1930

http://www.ncbi.nlm.nih.gov/pubmed/20953861

This report makes for a very interesting read and it looks like uncoupling proteins could be the answer for fat loss.

Brain administration of leptin causes deletion of adipocytes by apoptosis

http://www.ncbi.nlm.nih.gov/pubmed/9449655