Low-carbohydrate diet disrupts the association between insulin resistance and weight gain.

http://www.ncbi.nlm.nih.gov/pubmed/19439329

"the heavier animals that were fed LFD had impairment in insulin sensitivity, which was not observed in those fed LCD"

"The weight gain in animals fed LCD may be related to their greater caloric intake, lower levels of glucagon-like peptide-1, and higher protein consumption"

"The adoption of LCD promotes a unique metabolic state that prevents insulin resistance, even in guinea pigs that gained more weight."

"The association between weight gain and insulin resistance seems to be dependent on high carbohydrate intake"