Ketone bodies modulates body weight and hepatic insulin sensitivity

Central infusion of ketone bodies modulates body weight and hepatic insulin sensitivity by modifying hypothalamic leptin and insulin signaling pathways in type 2 diabetic rat

http://www.ncbi.nlm.nih.gov/pubmed/21652033

"In conclusion, mild ketosis by central infusion of ketones improves energy and glucose metabolism through the potentiation of leptin and insulin signaling in the hypothalamus of diabetic rats."